Jinyu Yuan Selected Research

N- (3- (4- chlorophenyl)- 2- (3- cyanophenyl)- 1- methylpropyl)- 2- methyl- 2- ((5- (trifluoromethyl)pyridin- 2- yl)oxy)propanamide

2/2009	Pharmacokinetics of digoxin in healthy subjects receiving taranabant, a novel cannabinoid-1 receptor inverse agonist.
1/2009	Influence of taranabant, an orally active, highly selective, potent cannabinoid-1 receptor (CB1R) inverse agonist, on ethinyl estradiol and norelgestromin plasma pharmacokinetics.
11/2008	Influence of taranabant, a cannabinoid-1 receptor inverse agonist, on pharmacokinetics and pharmacodynamics of warfarin.
6/2008	Multiple-dose pharmacokinetics, pharmacodynamics, and safety of taranabant, a novel selective cannabinoid-1 receptor inverse agonist, in healthy male volunteers.
4/2008	Safety, tolerability, pharmacokinetics, and pharmacodynamic properties of taranabant, a novel selective cannabinoid-1 receptor inverse agonist, for the treatment of obesity: results from a double-blind, placebo-controlled, single oral dose study in healthy volunteers.
1/2008	The acyclic CB1R inverse agonist taranabant mediates weight loss by increasing energy expenditure and decreasing caloric intake.

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Jinyu Yuan Research Topics

Disease

5	Renal Cell Carcinoma (Grawitz Tumor) 09/2014 - 08/2009
5	Obesity 01/2009 - 01/2008
3	Neoplasms (Cancer) 01/2017 - 02/2011
2	Weight Loss (Weight Reduction) 02/2009 - 01/2008
1	Breast Neoplasms (Breast Cancer) 01/2017
1	Diarrhea 01/2017
1	Neutropenia 01/2017
1	Peripheral Nervous System Diseases (PNS Diseases) 01/2017
1	Disease Progression 01/2017
1	Fatigue 03/2012
1	Brain Neoplasms (Brain Tumor) 02/2011
1	Vomiting 04/2008
1	Dizziness (Lightheadedness) 04/2008
1	Abdominal Pain (Pain, Abdominal) 04/2008
1	Headache (Headaches) 04/2008
1	Hiccup (Hiccups) 04/2008
1	Nausea 04/2008

Drug/Important Bio-Agent (IBA)

6	N- (3- (4- chlorophenyl)- 2- (3- cyanophenyl)- 1- methylpropyl)- 2- methyl- 2- ((5- (trifluoromethyl)pyridin- 2- yl)oxy)propanamideIBA 02/2009 - 01/2008
5	Sunitinib (Sutent)FDA Link 09/2014 - 08/2009
2	Pharmaceutical PreparationsIBA 02/2009 - 04/2008
2	CannabinoidsIBA 04/2008 - 01/2008
1	taxaneIBA 01/2017
1	Trastuzumab (Herceptin)FDA Link 01/2017
1	Monoclonal AntibodiesIBA 01/2017
1	Taxoids (Taxanes)IBA 01/2017
1	Biosimilar PharmaceuticalsIBA 01/2017
1	Digoxin (Digitek)FDA LinkGeneric 02/2009
1	Cardiac GlycosidesIBA 02/2009
1	Warfarin (Coumadin)FDA LinkGeneric 11/2008

Therapy/Procedure

3	Therapeutics 01/2017 - 01/2008
1	Drug Therapy (Chemotherapy) 01/2017
1	Aftercare (After-Treatment) 03/2012